IVF Medication UK: Gonal-f, Menopur, Cetrotide, Ovitrelle and How They Are Used

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When the medication plan for an IVF cycle arrives, it can feel like learning a new language overnight. Brand names, injection pens, mixing vials, fridge instructions and exact timings, all while trying to stay calm about the cycle itself.

This guide puts the most common IVF medicines in one place: what each one does, how it is given, how it should be stored, and the side effects to know about. It also explains how fertility prescriptions are dispensed and delivered so your medicines arrive before you need them. Everything clinical here comes from official UK product information or Pharmazon HomeCare's pharmacist-reviewed fertility guides. Your clinic's instructions always come first.

what medication is used for IVF in the UK? A typical IVF cycle uses stimulation injections to grow follicles, such as Gonal-f (follitropin alfa) or Menopur (menotrophin); medicines to prevent early ovulation, such as Cetrotide (cetrorelix) or ganirelix; a trigger injection, such as Ovitrelle (choriogonadotropin alfa), to mature the eggs before collection; and progesterone, such as Cyclogest pessaries, to support the womb lining after transfer. Storage varies: some must be refrigerated at 2 to 8°C, while others are kept at room temperature.

IVF Medication UK at a Glance

Stimulation (follicle growth)Gonal-f (follitropin alfa), Menopur (menotrophin)
Preventing early ovulationCetrotide (cetrorelix), ganirelix (e.g. Fyremadel)
Trigger injectionOvitrelle (choriogonadotropin alfa)
Luteal supportProgesterone, e.g. Cyclogest pessaries
How givenMostly injections under the skin; progesterone as pessaries, gel or injection
StorageVaries by product. Some at 2 to 8°C, some at room temperature
Main safety riskOvarian hyperstimulation syndrome (OHSS)

How IVF Medication Works

IVF medicines work in stages. Your clinic sets the protocol, doses and timings, which can change from scan to scan.

  1. Stimulation: hormone injections (FSH, sometimes with LH activity) help several follicles develop at once.
  2. Preventing early ovulation: a GnRH antagonist (or, in some protocols, an agonist) stops the eggs being released too soon.
  3. Trigger: a timed trigger injection completes egg maturation. Egg collection usually follows 34 to 36 hours later.
  4. Luteal support: progesterone, and sometimes oestrogen, supports the womb lining for embryo transfer.

For a class-by-class overview, including GnRH agonists and oestrogen, read our fertility medication guide.

Common IVF Medication Names in the UK

IVF medicines, how they are given and how they are stored
BrandActive ingredientUsed forForm and routeStorage (from the product information)
Gonal-fFollitropin alfaStimulationPre-filled pen, under the skinFridge (2 to 8°C) before opening; may be kept at up to 25°C for a single period of up to 3 months. After opening, 2 to 25°C for up to 28 days
MenopurMenotrophinStimulationPowder and solvent, mixed before use; into a muscle or under the skinDo not store above 25°C. Do not freeze. Use immediately after mixing
Cetrotide 0.25 mgCetrorelixPreventing early ovulationPowder and solvent; under the skin of the lower abdomenFridge (2 to 8°C); may be kept at up to 30°C for up to 3 months. Use immediately after mixing
FyremadelGanirelixPreventing early ovulationPre-filled syringe, under the skinNo special storage conditions
OvitrelleChoriogonadotropin alfaTrigger injectionPre-filled pen, under the skinFridge (2 to 8°C). Do not freeze. Use immediately after opening
CyclogestProgesteroneLuteal supportPessary, vaginal or rectalDo not store above 30°C

Storage details can differ between strengths and pack types. Always check the Patient Information Leaflet in your pack and follow your clinic's instructions.

Gonal-f (follitropin alfa)

Gonal-f is a recombinant FSH used to stimulate follicle development in women having assisted reproduction or with ovulation problems. It comes as a multidose pre-filled pen injected under the skin. Very common side effects listed in the product information include headache, ovarian cysts and injection site reactions.

Menopur (menotrophin)

Menopur contains menotrophin, which has both FSH and LH activity. It comes as a powder that is mixed with a solvent before injection, either into a muscle or under the skin. Common side effects include abdominal pain and bloating, nausea, headache and injection site reactions.

Cetrotide (cetrorelix) and ganirelix

Cetrotide is used for the prevention of premature ovulation in patients undergoing controlled ovarian stimulation. It is mixed and injected under the skin of the lower abdomen. Ganirelix products such as Fyremadel do the same job and come in a ready-to-use pre-filled syringe. Injection site reactions such as redness, swelling and itching are common.

Ovitrelle (choriogonadotropin alfa)

Ovitrelle is a trigger injection that brings about final follicular maturation before egg collection. Timing is critical, so take it at the time your clinic gives you. It must be kept in the fridge.

Cyclogest (progesterone)

Cyclogest pessaries are used for luteal phase support as part of assisted reproductive treatment. They can be used vaginally or rectally. Common side effects include sleepiness, abdominal discomfort and breast pain.

IVF Medication Side Effects

Common side effects across IVF medicines include bloating and abdominal discomfort, headaches, breast tenderness, mood changes and injection site reactions such as redness or bruising.

Ovarian hyperstimulation syndrome (OHSS)

OHSS is the main safety risk with fertility stimulation. The product information notes it can develop rapidly, within 24 hours to several days, and that the trigger injection plays a key role in it. Your clinic will monitor you for at least two weeks after the trigger.

Contact your clinic straight away, or seek urgent medical help, if you have:

  • Severe abdominal pain or swelling
  • Nausea or vomiting
  • Difficulty breathing
  • Visual disturbances

Report suspected side effects through the MHRA Yellow Card scheme.

How to Store IVF Medication

Getting storage right protects the medicine and your cycle. Our pharmacists' general guidance:

  • Refrigerated medicines go in the fridge at 2 to 8°C, away from the freezer compartment
  • Never freeze fertility injections
  • Keep medicines in their original packaging, away from light
  • Note the date any pen is first opened or taken out of the fridge, as time limits apply
  • Check each product's leaflet, because storage rules differ: for example, Menopur is stored below 25°C, while Ovitrelle must stay in the fridge

How Much Does IVF Medication Cost in the UK?

The cost of IVF medication depends on your protocol, the medicines and doses prescribed, and how many days of stimulation you need, so there is no single average price. Read our guide to IVF medication costs in the UK for what affects the price.

Fertility Medication Delivery in the UK

Because doses change from scan to scan and several medicines need to stay cold, many patients and clinics use IVF medication delivery rather than collecting in person.

How Pharmazon HomeCare dispenses your IVF prescription

  1. Your clinic issues a valid prescription and shares your planned start date.
  2. The prescription reaches us securely from your clinic.
  3. A GPhC-registered pharmacist checks it and confirms every item is in stock.
  4. Each medicine is packed to its own storage requirements, using validated cold-chain packaging at 2 to 8°C for refrigerated items.
  5. Your medicines are delivered by tracked delivery, timed to arrive before your first dose, with same-day delivery available in London and next-day delivery across the UK.

If your dose changes mid-cycle, your clinic sends a new prescription and we process it as a matter of priority.

Why Pharmazon HomeCare: A GPhC-registered pharmacy working with fertility clinics and consultants, including Harley Street and London clinics, with cold-chain delivery timed to your cycle and a London office at 8 Devonshire, W1G. Get in touch with our pharmacy team.

Questions to Ask Your Clinic About Your IVF Medication

  • Which medicines am I taking, and what does each one do?
  • When and how do I give each injection, and who will show me?
  • Which medicines need the fridge, and how long can they be out of it?
  • What should I do if I miss or delay a dose?
  • What are the signs of OHSS, and who do I call out of hours?
  • When will my medicines be delivered, and what if my dose changes?

Frequency Asked Question

IVF usually involves stimulation injections such as Gonal-f or Menopur, medicines to prevent early ovulation such as Cetrotide or ganirelix, a trigger injection such as Ovitrelle, and progesterone such as Cyclogest. Pharmazon HomeCare dispenses fertility prescriptions from UK clinics.

 

Gonal-f contains follitropin alfa, a recombinant FSH, in a ready-to-use pen. Menopur contains menotrophin, which has both FSH and LH activity, and is a powder mixed with solvent before injection. Your clinic decides which suits your protocol.

 

Cetrotide (cetrorelix) prevents premature ovulation during ovarian stimulation, so the eggs are not released before collection.

 

At the exact time your clinic gives you, usually 34 to 36 hours before egg collection. Timing is critical, so set a reminder.

 

Some do. Gonal-f, Cetrotide and Ovitrelle are stored at 2 to 8°C, with some allowances out of the fridge, while Menopur is stored below 25°C and Cyclogest below 30°C. Always check your leaflet. Pharmazon HomeCare delivers refrigerated medicines in validated cold-chain packaging.

 

Your clinic’s nurse team. Every medicine is supplied with its Patient Information Leaflet, and our pharmacists can answer questions about storage and delivery.

Before opening, Gonal-f may be kept at up to 25°C for a single period of up to 3 months. Once opened, it can be stored between 2 and 25°C for up to 28 days.

 

Severe abdominal pain or swelling, nausea or vomiting, difficulty breathing or visual disturbances. Contact your clinic straight away if you notice any of these.

 

Bloating, abdominal discomfort, headaches, breast tenderness, mood changes and injection site reactions are common. Your clinic will monitor you throughout the cycle.

 

Yes, with a valid prescription. Pharmazon HomeCare delivers IVF medication by tracked delivery timed to your cycle, with same-day delivery in London and next-day delivery across the UK.

 

Your clinic sends a new prescription, and Pharmazon HomeCare processes it as a priority so you have what you need for your next dose.

 

Yes. Pharmazon HomeCare uses plain, discreet outer packaging with tracked delivery.

 

Conclusion

An IVF cycle asks a lot of you, and the medication plan is one of the most detailed parts of it. Knowing what each medicine does, how to store it and which side effects need a call to your clinic takes some of the uncertainty out of each step, so you can focus on the cycle itself.

Have an IVF prescription? Get in touch with our pharmacy team to arrange dispensing and cold-chain delivery.

References

  1. GONAL-f 300 IU/0.48 mL solution for injection in pre-filled pen, Summary of Product Characteristics. emc. medicines.org.uk/emc/product/69/smpc
  2. MENOPUR 150 IU powder and solvent for solution for injection, Summary of Product Characteristics. emc. medicines.org.uk/emc/product/4260/smpc
  3. Cetrotide 0.25 mg powder and solvent for solution for injection, Summary of Product Characteristics. emc. medicines.org.uk/emc/product/1605/smpc
  4. Ovitrelle 250 micrograms solution for injection in pre-filled pen, Summary of Product Characteristics. emc. medicines.org.uk/emc/product/2806/smpc
  5. Cyclogest 400mg pessaries, Summary of Product Characteristics. emc. medicines.org.uk/emc/product/5569/smpc
  6. Fyremadel 0.25 mg/0.5 ml solution for injection, Summary of Product Characteristics. emc. medicines.org.uk/emc/product/2681/smpc
  7. MHRA Yellow Card scheme. yellowcard.mhra.gov.uk

Pharmazon HomeCare. GPhC-registered pharmacy: 9012756. Superintendent Pharmacist: Mohammed Abou Daya (GPhC: 2083143).

AG
Archna Gudka, Pharmacist
GPhC Registration No. 2059368  ·  Reviewed: June 2026  ·  Not medical advice
UK Registered Clinician Weight-Loss Medication Specialist GLP-1 Dispensing Expertise Verify GPhC Registration

Reviewed by Archna Gudka, a GPhC-registered pharmacist with over two decades of experience in pharmacy, including 18 years in community pharmacy providing front-line patient care. At Pharmazon HomeCare, an ADHD specialist pharmacy, she has spent the past three years developing her clinical expertise in the management of ADHD and other neurodevelopmental conditions, supported by additional specialist training from the UK Adult ADHD Network (UKAAN). Her areas of clinical focus include ADHD care, neurodevelopmental support, weight management, and evidence-based, patient-centred pharmacy practice. This content is provided for general information only and should not replace personalised advice from your prescribing clinician or pharmacist. Next review: December 2026.